Abstract O-acetylation is a common modification of sialic acids that has been implicated in a multitude of biological and disease processes.A lack of analytical methods that can determine exact structures of sialic acid variants is a hurdle to determine roles of distinct O-acetylated sialosides.Here, we describe a drift tube ion mobility-mass spect
IntroductionHarvest time represents one of the crucial factors concerning the quality of alpine green tea.At present, the mechanisms of the tea quality changing with harvest time have been unrevealed.MethodsIn the current study, fresh tea leaves (qmlc and gylc) and processed leaves (qmgc and gygc) picked during Qingming Festival and Guyu Festival w
The paralogous genes INCURVATA11 (ICU11) and CUPULIFORMIS2 (CP2) encode components of the epigenetic machinery in Arabidopsis and belong to the 2-oxoglutarate and Fe (II)-dependent dioxygenase superfamily.We previously inferred unequal functional redundancy between klaire labs ashwagandha ICU11 and CP2 from a study of the synergistic phenotypes of
Abstract Objective Competition among trials for patient enrollment can impede recruitment.We hypothesized that this occurred early in the COVID-19 pandemic, when an unprecedented number of clinical trials were launched.We performed a simple and multivariable regression analysis evaluating the relationship between the proportion of SARS-CoV-2 invest
Social media and other forms of volunteered geographic information (VGI) are used frequently as a source of fine-grained big data for research.While employing geographically referenced social media data for a wide array of purposes has become commonplace, the relevant scales over which these data apply to is typically unknown.For researchers to use